Open Access Open Access  Restricted Access Subscription Access
Total views : 1197

HIV and Cancer

Affiliations

  • Department of Medical and Pediatric Oncology, The Gujarat Cancer and Research Institute., India
  • Department of Medical and Pediatric Oncology, The Gujarat Cancer and Research Institute., India

Abstract


Malignancies in Human Immunodeficiency Virus (HIV) are divided into AIDsdefining and non AIDs-defining. In the Highly Active Antiretroviral Therapy (HAART)-era the incidence of non AIDs-defining malignancies are increasing with better outcome as a result of improved CD4 counts and immune reconstitution, still cancer remains an important cause of death in HIV patients.

Full Text:

 |  (PDF views: 15)

References


  • Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and Adults, MMWR. Atlanta, Centers for Disease Control, 1992.
  • Lundgren JD, Babiker A, El-Sadr W, et al. Inferior clinical outcome of the CD4+ cell count-guided antiretroviral treatment interruption strategy in the SMART study: role of CD4+ Cell counts and HIV RNA levels during follow-up. J Infect Dis. 2008;197:1145.
  • Adolescents PoAGfAa: Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents., in Services DoHaH (ed), 2009, pp 1–161.
  • Bonnet F, Burty C, Lewden C, et al. Changes in cancer mortality among HIV-infected patients: the Mortalite 2005 Survey. Clin Infect Dis. 2009;48:633.
  • Dalgleish A, Beverley P, Clapham P et al. The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus. Nature. 1984; 312: 20–4
  • Klatzmann D, Champagne E, Chamaret S et al. T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV. Nature. 1984; 312: 24–7.
  • Yarchoan R, Uldrick TS, Little RF. AIDS-Related Malignancy. Principles & Practice of Oncology. 9th ed.Ch141.Lippincott;2011:2099-2111.
  • Bower M, Nelson M, Young AM, et al. Immune reconstitution inflammatory syndrome associated with Kaposi’s sarcoma. J Clin Oncol. 2005;23:5224.
  • Uldrick TS, Polizzotto M, O’Mahony D, et al. Rituximab Combined with Liposomal Doxorubicin (R-Dox) in HIV-Infected Patients with Severe Kaposi Sarcoma-associated Herpes Virus (KSHV) – associated Multicentric Castleman Disease (MCD). Presented at: the 12th International Conference on Malignancies in AIDS and Other Acquired Immunodeficiencies:Basic, Epidemiologic, and Clinical Research; April 26, 2010; Bethesda, MD.
  • Levine AM. Lymphoma complicating immunodeficiency disorders. Ann Oncol. 1994; 5(Suppl 2):29.
  • Morton LM, Wang SS, Devesa SS, et al. Lymphoma incidence patterns by WHO subtype in the United States, 1992–2001. Blood. 2006; 107:265.
  • Dunleavy K, Little RF, Pittaluga S, et al. The role of tumor histogenesis, FDG-PET, and short course EPOCH with dose-dense rituximab (SC-EPOCH-RR) in HIV-associated diffuse large B-cell lymphoma.Blood. 2010;115(15):3017.
  • Tirelli U, Errante D, Dolcetti R, et al. Hodgkin's disease and human immunodeficiency virus infection: clinicopathologic and virologic features of 114 patients from the Italian Cooperative Group on AIDS and Tumors. J Clin Oncol. 1995;13:1758.
  • Workowski RA, Benman SM. Sexually transmitted diseases treatment guidelines, 2006. MMWR Morb Mortal Wkly Rep. 2006;55(RR11):1.
  • Goldie SJ, Freedberg KA, Weinstein MC, et al. Cost effectiveness of human papillomavirus testing to augment cervical cancer screening in women infected with the human immunodeficiency virus. Am J Med. 2001;111:140.
  • Minkoff H, Zhong Y, Burk RD, et al. Influence of adherent and effective antiretroviral therapy use on human papillomavirus infection and squamous intraepithelial lesions in human immunodeficiency virus-positive women. J Infect Dis. 2010;201:681.
  • Frisch M, Biggar R J, Goedert J J. Human papillomavirus-associated cancers in patients with human immunodeficiency virus infection and acquired immunodeficiency syndrome. J Natl Cancer Inst.2000;92:1500.
  • Silverberg MJ, Abrams DI. AIDS-defining and non-AIDS-defining malignancies: cancer occurrence in the antiretroviral therapy era. Curr Opin Oncol.2007;19:446.
  • Mosthaf FA, Hanhoff NJ, Goetzenich A, et al. High incidence of non-AIDS-defined cancers among HIVinfected patients in Germany: analysis of data collected over a period of 3 years. Dtsch Med Wochenschr.2006;131:1849.
  • Bonnet F, Burty C, Lewden C, et al. Changes in cancer mortality among HIV-infected patients: the Mortalite 2005 Survey. Clin Infect Dis. 2009;48:633.

Refbacks

  • There are currently no refbacks.