Mpox Inactivated in Just 60 Seconds Using Σ-MM™ and a Patient-Friendly Collection Swab

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Following the global Mpox outbreak in 2022, there has been a pressing need for safer and more efficient methods to transport and test virus samples, particularly in regions with limited biological containment. Addressing this need, the innovative Σ-MM™ medium and Soft Touch Foam Swab have emerged as pivotal advancements in diagnostic testing, ensuring both patient comfort and sample safety.

Mpox, caused by the Mpox virus—a DNA virus related to smallpox—has recently surged outside its usual endemic regions. Common symptoms include fever, headaches, muscle aches, and a distinctive rash that develops into fluid-filled blisters. While often mild and self-limiting, Mpox can be severe, especially in immunocompromised individuals. Accurate and timely diagnosis is essential for effective management and to prevent further spread.

As reported by news-medical.net, testing Mpox poses unique challenges due to its resistance to many disinfectants and its environmental stability. Ensuring samples are safely inactivated for transport, while preserving the integrity of the viral DNA for accurate identification, is crucial. The Σ-MM™ transport medium addresses this by effectively inactivating a range of microorganisms, including RNA viruses like Influenza and SARS-CoV-2. Research by the Liverpool School of Tropical Medicine (LSTM) has confirmed that Σ-MM™ can also inactivate the Mpox virus, doing so in just 60 seconds—30 times faster than other inactivation methods currently available.

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In the LSTM study, Σ-MM™ demonstrated complete inactivation of the Mpox virus across different conditions and lots, with no viral plaques detected in samples, while control samples retained significant viral loads. This effectiveness ensures safe transport for qPCR diagnostics, which are critical for accurate Mpox testing.

The Soft Touch Foam Swab complements Σ-MM™ by providing a patient-friendly option for sample collection, particularly from painful Mpox lesions. Its gentle, non-invasive design ensures comfort and preserves sample integrity, which is crucial for reliable testing.

Together, Σ-MM™ and the Soft Touch Foam Swab offer a comprehensive solution for safe, comfortable sample collection and transport. As Mpox continues to challenge public health, these innovations represent a significant advancement in managing the outbreak and safeguarding both patients and healthcare workers. Integrating these tools into routine diagnostic practices could play a vital role in controlling future outbreaks and enhancing responses to infectious diseases.