A study presented at the American Headache Society’s 66th annual scientific meeting has found a significant correlation between rising temperatures and increased migraine attacks. Researchers indicated that as temperatures rise, the likelihood of migraine attacks also increases.
Weather changes, particularly hot temperatures, are commonly recognized as migraine triggers. High temperatures can lead to dehydration, reducing blood flow to the brain and triggering pain. Additionally, heat can increase physical stress and discomfort, heightening sensitivity in individuals prone to migraines. The body’s response to heat, such as dilated blood vessels and changes in pressure, also contributes to the onset of migraine headaches.
The study explored the effectiveness of Fremanezumab, a monoclonal antibody, in preventing headaches caused by high temperatures. Fremanezumab works by targeting and inhibiting calcitonin gene-related peptide (CGRP), a protein involved in migraine pain transmission. By blocking CGRP, Fremanezumab reduces the frequency and severity of migraine attacks, offering relief to those with weather-triggered headaches. This treatment can stabilize the neurological response to environmental factors, such as hot temperatures, and significantly improve the quality of life for migraine sufferers.
As reported by Medical Dialogues, researchers analyzed 71,030 daily diary records from 660 migraine patients, correlating the data with regional weather information. They found that for every 0.12-degree Celsius increase in temperature, there was a 6 percent increase in headache occurrences. Notably, during Fremanezumab treatment periods, this association disappeared entirely. If future studies confirm these results, Fremanezumab could become a valuable therapy for individuals with weather-triggered migraines.