Modern IVF techniques are improving success rates while reducing the chances of multiple pregnancies, according to a major study presented at the 42nd Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE). The research analysed outcomes of 18,396 women undergoing their first IVF cycle across seven Australian fertility clinics between 2012 and 2021.
The study found that modern IVF practices achieved a cumulative live birth rate of 68.2% over three treatment cycles. Doctors used single embryo transfer in 95.3% of cases, while the multiple birth rate remained low at 2.9%.
Advances in IVF Technology Drive Better Results
Researchers linked the improved outcomes to advances such as blastocyst culture, embryo vitrification, freeze-all strategies, and improved frozen embryo transfer methods. These techniques help specialists select and preserve embryos more effectively, increasing the chances of a successful pregnancy.
As per Medical Dialogues, the findings show that modern IVF approaches can deliver better results without relying on the transfer of multiple embryos, which can increase the risk of twin and triplet pregnancies.
Success Rates Differ by Age Group
The study also showed that a woman’s age significantly influences IVF outcomes. Women below 35 years achieved an 84.5% cumulative live birth rate, while success rates gradually declined among older age groups. Women aged 35–37 recorded a 74.4% rate, those aged 38–40 achieved 57.7%, and women aged 41–42 recorded 30.1%.
Single Embryo Transfer Becomes the Preferred Approach
Earlier IVF practices often involved transferring more than one embryo to improve pregnancy chances. However, modern laboratory techniques now allow doctors to achieve strong success rates while transferring a single embryo, reducing complications linked to multiple pregnancies.
Overall, the study highlights how continuous improvements in IVF technology and clinical practices are helping patients achieve safer pregnancies and better outcomes.