A multidisciplinary team at Wockhardt Hospitals, Mumbai Central successfully managed and delivered a healthy baby for a 48-year-old woman with a 36-week IVF–ICSI pregnancy, despite numerous maternal and fetal risk factors.
A Complex Journey to Conception
The patient, who previously had one abortion, conceived through IVF with Intracytoplasmic Sperm Injection (ICSI) on December 30, 2024. Both partners carried significant reproductive risks. The male partner had severe oligospermia, while the mother presented with advanced maternal age, fibroid uterus, thin endometrium, adenomyosis, low AMH levels, and an ovarian cyst.
To prepare for embryo implantation, she underwent hysteroscopic surgery with fundal and lateral metroplasty in November 2024. This procedure helped create a favorable uterine cavity, and she conceived successfully in the very first IVF cycle.
Managing High-Risk Pregnancy Challenges
As per the press release, the pregnancy involved multiple complications that required careful, continuous supervision:
- Recurrent first- and second-trimester bleeding, which necessitated complete bed rest and progesterone support.
• Pregnancy-induced hypertension, managed through continuous monitoring and antihypertensive therapy.
• Gestational diabetes, addressed through a multidisciplinary approach and regular follow-ups.
• Clot-prevention therapy, including Low Molecular Weight Heparin (LMWH).
• Ophthalmology and systemic evaluations to monitor hypertension-related complications.
Despite these challenges, the clinical team stabilized her condition through timely interventions, medication support, and strict surveillance of both mother and fetus.
Emergency at 35 Weeks: PPROM and a Rare Intraoperative Complication
At 35.4 weeks, the patient experienced premature rupture of membranes (PPROM). Doctors promptly administered medication to support fetal lung maturity and prepared her for a planned C-section.
However, during surgery, a rare and life-threatening complication occurred—uterine inversion caused by an adherent placenta. The team acted with urgency, manually corrected the inversion, and stabilized the mother before proceeding.
A Safe Delivery and Strong Recovery
A healthy male baby was delivered, cried immediately, and required no NICU admission. Both mother and baby recovered well and were discharged in stable condition five days later.
Expert Insights on Managing Extremely High-Risk Pregnancies
Dr. Gandhali Deorukhkar, Consultant – Obstetrics & Gynaecology at Wockhardt Hospitals, emphasized the complexity of this case. She said:
“Pregnancy at 48 with multiple risk factors demands exceptional precision, constant reassessment, and multidisciplinary teamwork. From conception through delivery, this journey involved overcoming bleeding, hypertension, diabetes, and even an intraoperative uterine inversion. Our ability to anticipate complications, provide vigilant care, and act swiftly at critical moments ensured both mother and child are safe today. This case highlights how advanced reproductive medicine and evidence-based obstetric care can achieve excellent outcomes even in extremely high-risk pregnancies.”
A Comprehensive High-Risk Obstetrics Program
Wockhardt Hospitals’ high-risk obstetrics program brings together obstetricians, physicians, and fetal medicine specialists to manage complex pregnancies—especially those involving advanced maternal age and assisted reproductive technologies. The team prioritizes safety, continuity of care, and compassionate support for both mother and family throughout the pregnancy journey.