A new clinical study has been launched to determine whether customised foot orthoses can improve knee alignment, reduce pain and enhance mobility in individuals with flat feet and medial compartment knee osteoarthritis. Announced on the International Day of Persons with Disabilities, the study focuses on how specially designed insoles may help prevent tibiofibular rotation during weight-bearing and support long-term functional independence.
Advanced Standing MRI to Capture Real-Life Knee Mechanics
A key feature of this research is the use of standing weight-bearing MRI, which allows clinicians to examine the knee under natural load-bearing conditions. During the first visit, participants will undergo scans in full extension and at 30-degree flexion—both with and without the customised orthosis. They will undergo repeat scans after six months. Additionally, the researchers will include a comparison group with healthy knees to strengthen the study’s findings.
Collaboration Between PDU Institute and Mahajan Imaging
As reported by The Week, the study is a joint initiative of the Pandit Deendayal Upadhyay Institute for Persons with Disabilities (Ministry of Social Justice and Empowerment) and Mahajan Imaging and Labs. The collaboration aims to advance evidence-based orthotic interventions through high-quality clinical imaging.
Experts Highlight the Study’s Potential
Padma Shri Dr. Harsh Mahajan, founder and chairman of Mahajan Imaging and Labs, emphasized the study’s core goal. He said it aims to translate advanced imaging insights into practical solutions that improve mobility. He noted that standing MRI technology helps clinicians understand how personalised orthoses can correct knee alignment and redistribute pressure.
Rising Burden of Knee Osteoarthritis in India
The official statement also highlighted a growing health concern. Nearly one in three to four adults over 40 in India may suffer from symptomatic knee osteoarthritis, often aggravated by misalignment linked to flat feet. This underscores the urgent need for effective, non-surgical interventions.
Objective Data to Strengthen Orthotic Care
Senior consultant radiologist Dr. Geetanjali Nanda explained that the study will generate objective data. It will measure shinbone rotation, joint space and ligament health to assess knee stability and the effectiveness of customised insoles.
Kabir Mahajan, Chief Operating Officer at Mahajan Imaging and Labs, said the research aligns with broader efforts to advance non-surgical solutions. He added that it also strengthens evidence-based orthotic care. This is supported through the Centre for Advanced Research in Imaging, Neurosciences and Genomics (CARING).
This study marks a significant step toward developing personalised, effective, and non-invasive approaches to managing knee osteoarthritis in India.