The Asian Institute of Nephrology and Urology (AINU), a pioneer in advanced urological care, has achieved a major surgical milestone by performing a pioneering Ureter reconstruction using tissue from the inside of the mouth (buccal mucosa) to rebuild a damaged ureter. The innovative surgery, conducted on a 38-year-old male patient from Nepal, highlights the hospital’s expertise in minimally invasive and regenerative urology.
Complex Case from Nepal
As per the press release, the patient, who had suffered kidney issues since childhood, was living with a single functioning kidney after the other became severely shrunken. Recently, he developed stones in the upper portion of the ureter of his only functional kidney. While doctors in Nepal were performing laser treatment to remove his stones, they accidentally damaged his ureter, further narrowing the already delicate structure. As a result, he developed severe urinary complications, and doctors referred him to AINU in Hyderabad for advanced management.
Innovative Reconstructive Surgery
Dr. C. Mallikarjuna, Managing Director, Chief Consultant Urologist, and Robotic Surgeon at AINU, led the complex reconstructive procedure. “After thorough evaluation, we decided to use buccal mucosa tissue from inside the patient’s mouth to repair the damaged ureter. The buccal mucosa is a thin, flexible tissue that, when grafted onto the damaged portion, adheres around the edges—similar to patching a punctured tube—thereby restoring the ureter’s function,” he explained.
This intricate technique allowed surgeons to rebuild the narrow ureter effectively and restore normal urinary flow, saving the patient’s only functioning kidney.
Expanding the Use of Buccal Mucosa in Urology
Traditionally, urologists have used buccal mucosa for urethral reconstruction, especially in cases where infections or trauma caused damage. However, applying it to ureteral reconstruction marks a new frontier in urological surgery. “While this tissue has been used for repairing the urethra, its use in ureter reconstruction is a significant innovation,” Dr. Mallikarjuna noted. “At AINU, we now perform such complex procedures laparoscopically or robotically instead of through open surgery, ensuring faster recovery and less discomfort for patients.”
Understanding the Difference: Ureter vs. Urethra
Dr. Mallikarjuna clarified that while both structures are part of the urinary tract, their functions differ. The ureters transport urine from the kidneys to the bladder, whereas the urethra carries urine from the bladder to the outside of the body. Because the ureters are much narrower, their reconstruction poses greater challenges than that of the urethra.
Role of Technology in Modern Urology
Emphasizing the impact of advanced technology, Dr. Mallikarjuna said, “Technology is always a boon. The treatment of kidney stones has transformed dramatically with laser technology. It minimizes patient discomfort and offers greater precision. However, it must be used carefully to prevent complications.”
He added that while urethral reconstruction is relatively easier due to its wider diameter, ureteral reconstruction demands far greater precision. “With the use of buccal mucosa grafts and minimally invasive techniques, we can now overcome these challenges successfully,” he concluded.
Summary
This landmark case reinforces AINU’s leadership in adopting cutting-edge, patient-centered approaches in urology. By integrating regenerative tissue grafting with robotic and laparoscopic precision, the hospital continues to set new benchmarks in treating complex urological conditions.




















