A 28-year-old woman with Sjögren’s syndrome-associated ganglionopathy and progressive neurological disability has shown encouraging functional improvement following cell-based therapy and rehabilitation at StemRx Hospital & Research Centre.
Progressive Neurological Disability
Navi Mumbai: Taniya Modak Paik from Kolkata first developed an unusual pulling sensation while walking in 2018. Over the years, she developed stiffness, weakness, numbness and balance problems that progressively affected her mobility. By 2023, she struggled with routine activities and eventually became wheelchair-dependent.
A muscle biopsy in December 2023 confirmed autoimmune myositis. Later, she was diagnosed with Sjögren’s syndrome, which explained her neurological symptoms along with severe dryness of the eyes and mouth and loss of taste. She underwent plasmapheresis in 2024 and received monoclonal antibody therapy and Rituximab in 2025. However, her condition continued to worsen.
Personalised Treatment
She subsequently consulted Dr. Pradeep Mahajan, Regenerative Medicine Expert and Founder of StemRx Hospital & Research Centre. As per the press release, the patient underwent a personalised regenerative medicine and rehabilitation programme based on her neurological condition and functional limitations.
The treatment included cell-based therapy, targeted exosomes, mitochondrial therapy, physiotherapy and nutritional support. The programme focused on supporting tissue repair, improving cellular energy, reducing inflammation and restoring muscle strength and mobility.
Encouraging Recovery
Within 15 days, Taniya reported reduced oral dryness and gum bleeding, easier swallowing, less back pain and muscle stiffness, and improved mobility. She can now get up from a chair more easily and walk with the support of a stick.
Dr. Mahajan explained that Sjögren’s syndrome can sometimes affect the nervous system and cause ganglionopathy, leading to sensory loss, poor balance, weakness and difficulty walking. He emphasised that early diagnosis, appropriate treatment and long-term rehabilitation are important for managing such complications.
The patient has recovered well and has been discharged with advice to continue physiotherapy and regular follow-up.
Renewed Hope
Taniya said the improvement in her ability to stand and walk with support has restored her confidence and given her renewed hope after years of progressive disability.